كتاب Quantitative Trait Loci. Methods and Protocols-Humana Pressالكتب العلمية

كتاب Quantitative Trait Loci. Methods and Protocols-Humana Press

نبذه عن الكتاب: A classical case-control study design is frequently used in genetic epidemiology to investigate the association between genotype and the presence or absence of disease. Association studies can also be useful in the investigation of quantitative traits. The aim of such studies is to test for association at the population level between the quantitative trait and genotype at a particular locus. Whether investigating qualitative or quantitative traits, such studies depend on the prior identification of a candidate gene or genes. The genotyped locus could either be a polymorphism within a potentially trait-affecting gene or a marker in linkage disequilibrium with such a gene. Currently, screening of the whole genome is only feasible using linkage analysis, which is discussed elsewhere, because linkage extends over much greater distances than does linkage disequilibrium. Quantitative trait association studies are based on a sample of unrelated subjects from the population. Various sampling designs are possible, including random sampling and sampling on the basis of an extreme phenotype. The advantages and disadvantages of these alternative designs are discussed. The basic method of analysis is called analysis of variance (see Subheading 2.1.) a standard statistical technique for testing for differences in mean between two or more groups, on the basis of the comparison of between- and withingroup variances. An alternative if subjects are sampled on the basis of extreme phenotype is to compare genotypes between groups with high and low trait values (see Subheading 2.2.).
Nicola J. Camp Angela Cox - ❰ له مجموعة من الإنجازات والمؤلفات أبرزها ❞ Quantitative Trait Loci. Methods and Protocols-Humana Press ❝ ❱
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وصف الكتاب : نبذه عن الكتاب:

A classical case-control study design is frequently used in genetic epidemiology to investigate the association between genotype and the presence or absence
of disease. Association studies can also be useful in the investigation of quantitative traits. The aim of such studies is to test for association at the population
level between the quantitative trait and genotype at a particular locus. Whether
investigating qualitative or quantitative traits, such studies depend on the prior
identification of a candidate gene or genes. The genotyped locus could either
be a polymorphism within a potentially trait-affecting gene or a marker in
linkage disequilibrium with such a gene. Currently, screening of the whole
genome is only feasible using linkage analysis, which is discussed elsewhere,
because linkage extends over much greater distances than does linkage disequilibrium.
Quantitative trait association studies are based on a sample of unrelated
subjects from the population. Various sampling designs are possible, including
random sampling and sampling on the basis of an extreme phenotype. The
advantages and disadvantages of these alternative designs are discussed.
The basic method of analysis is called analysis of variance (see Subheading
2.1.) a standard statistical technique for testing for differences in mean between
two or more groups, on the basis of the comparison of between- and withingroup variances. An alternative if subjects are sampled on the basis of extreme
phenotype is to compare genotypes between groups with high and low trait
values (see Subheading 2.2.).

سنة النشر : 2002م / 1423هـ .
عدد مرات التحميل : 3655 مرّة / مرات.
تم اضافته في : السبت , 25 يناير 2020م.
حجم الكتاب عند التحميل : 2.161 .

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Biologically

Biology is a natural science that is concerned with the study of life, its various forms and its function, how these organisms interact with each other and with the surrounding environment. The word biology in Greek is made up of two words: bio (βίος) meaning life. And loggia (-λογία) means science or study. Biology: the similarity of vegetation and animal cover on the edges of the African and American states, and the existence of the same fossil.


Branches of biology
Biology is an ancient science thousands of years old and modern biology began in the nineteenth century. This science has multiple branches. Among them are:

Anatomy
Botany
Biochemia
Biogeography
Biofisia
Cytology or cell science
Ecology or environmental science

 

 

نبذه عن الكتاب:

A classical case-control study design is frequently used in genetic epidemiology to investigate the association between genotype and the presence or absence
of disease. Association studies can also be useful in the investigation of quantitative traits. The aim of such studies is to test for association at the population
level between the quantitative trait and genotype at a particular locus. Whether
investigating qualitative or quantitative traits, such studies depend on the prior
identification of a candidate gene or genes. The genotyped locus could either
be a polymorphism within a potentially trait-affecting gene or a marker in
linkage disequilibrium with such a gene. Currently, screening of the whole
genome is only feasible using linkage analysis, which is discussed elsewhere,
because linkage extends over much greater distances than does linkage disequilibrium.
Quantitative trait association studies are based on a sample of unrelated
subjects from the population. Various sampling designs are possible, including
random sampling and sampling on the basis of an extreme phenotype. The
advantages and disadvantages of these alternative designs are discussed.
The basic method of analysis is called analysis of variance (see Subheading
2.1.) a standard statistical technique for testing for differences in mean between
two or more groups, on the basis of the comparison of between- and withingroup variances. An alternative if subjects are sampled on the basis of extreme
phenotype is to compare genotypes between groups with high and low trait
values (see Subheading 2.2.).

Biology
Human biology
Who is the founder of biology?
The importance of biology
Areas of work in the field of biology
Theories of biology
Research on biology for the first grade of secondary school
Human biology

 



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تحميل Quantitative Trait Loci. Methods and Protocols-Humana Press
Nicola J. Camp
Angela Cox
Nicola J. Camp Angela Cox



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